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Although SPME has been used to predict the toxicity or bioconcentration of hydrophobic organic contaminants in complex matrices, such as soil and sediment 36,37 , determining the ionizable compound content by SPME is difficult, and SPME cannot simulate the ion-trapping model

More than 30 units means larger injection volumes, which some researchers find uncomfortable or impractical

Although a number of creative and successful approaches in animal models have been employed to deliver growth factors (e.g