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Acts as negative regulator of NF-kappa-B-dependent transcription by promoting the ubiquitination and stabilization of the NF-kappa-B inhibitor TNFAIP3
which are linked by disulfide bonds to form a heterodimeric glycoprotein
MB10608-100
Regulates the circadian expression of the core clock components NR1D1 and ARNTL/BMAL1
Catalogue Number: CEK1373
ZAP70 Monoclonal Antibody-MB11797 Size:50µl Acts as negative regulator ofZAP70 Monoclonal Antibody Sizes: 50l, 100l Catalogue Numbers: MB11797 50, MB11797 100 Product: 50mM Tris Glycine(pH 7. 4), 0. 15M NaCl, 40% Glycerol, 0. 01% Sodium azide and 0. 05% BSA Swiss Prot: P43403 Host: Rabbit Reactivity: Human, Mouse, Rat Applications: WB,IP All Applications: WB: 1 500 1 1000 IP: 1 20 Background: The Syk family protein tyrosine kinase Zap 70 is expressed in T and NK cells and plays a critical role in mediating T cell