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Loss of AJs can cause decreased BBB integrity and increased permeability

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This correlates with DSIP's documented promotion of delta wave (slow-wave) sleep

Even though some micronutrients, such as Ca, Mg, Fe, folic acid, and Vit D, have been shown by some researchers to exert a protective effect in sleep [14, 15, 33, 34] while K reportedly has the opposite effect [35], our study did not find any associations between these micronutrients and insomnia