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33 Briefly, nicotine, NOX, Nic-Gluc, HPBA, cotinine, COX, Cot-Gluc, 3HC, and 3HC-Gluc were detected using a UPLC (Waters Acquity

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In a transgenic mouse model that overproduces active renin, overactivation of the RAAS was shown to promote colitis by stimulating intestinal epithelial cell apoptosis and mucosal TH17 responses (Shi et al., 2016)

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