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Yuan C, Parekh H, Allegra C, George TJ, Starr JS (2019) 5-FU induced cardiotoxicity, case series and review of the literature

In addition, it was noted that both BP and DOX work synergistically and upregulate the expression of apoptotic genes and proteins and eventually decrease the volume of tumor cells while decreasing the level of nitric oxide and estrogen and downregulating the level of pro-inflammatory cytokines in mice models with induced 4 T1 breast tumors

doi:10.1016/j.rbmo.2018.09.016

Di ChiacchioIMGmez-AbenzaEPaivaIMde AbreuDJRodrguez-VidalJFCarvalhoEEet al

In some embodiments, the otic formulation or composition comprises about 0.8% by weight of the poloxamer