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Reactive oxygen species (ROS), together with reactive nitrogen species (RNS), represent the most important prooxidants whose excessive accumulation leads to oxidative stress (OxS) and molecular damage ( ROS are crucial in thyroid function because they are essential in the initial stages of thyroid hormone synthesis during iodide oxidation ( Aerobic organisms have evolved multiple antioxidant and repair systems for protection against OxS

Li W, Qu G, Choi SC, Cornaby C, Titov A, Kanda N, et al

doi: 10.1016/j.fertnstert.2020.04.002 30 ZhangHLiCWenDLiRLuSXuRet al

CW, GS and CS were responsible for the study coordination, proband care and the sample collection