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Tobacco Quality : Premium cigars use aged, long-leaf filler, while 7-Eleven brands often use chopped scraps for a harsher taste

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A separate study also found protein levels of IL-6 and IL-8 to be increased in co-cultured primary gingival epithelial cells and fibroblasts in response nicotine-containing e-cigarette exposure and MCP-1 and TNF protein concentrations to be elevated independent of nicotine content (90)

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