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doi: 10.3389/fimmu.2026.1794782 Received 23 January 2026 Revised 17 February 2026 Accepted 20 February 2026 Published 05 March 2026 Volume 17 - 2026 Edited by Robson Coutinho-Silva, Federal University of Rio de Janeiro, Brazil Reviewed by Bingbing Sun, Dalian University of Technology, China Hui-chen Lo, Fu Jen Catholic University Libraries, Taiwan Updates Copyright 2026 Yang, Xu, Zhang, Xiao, Lu, Chen, Yang, Xie and Li

225 , 226 While uricosuric agents are generally well-tolerated, it is crucial to acknowledge that benzbromarone and probenecid may be associated with certain adverse effects

& Aravindakshan, S

DSIP (delta sleep-inducing peptide) was first isolated from rabbit cerebral venous blood in 1974 and has accumulated a small but published clinical-trial base most notably a 1992 Schneider-Helmert study showing improved sleep with DSIP infusion in chronic insomniacs over 7 successive nights and earlier studies showing improved sleep duration in middle-aged chronic insomniacs

14 : 8592 Cuenod C-A, Kaplan DB, Michot J-L, Jehenson P, Leroy-Willig A, Forette F et al