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Encouragingly, many EDS patients who have carefully weighed these factors and proceeded with therapy have found the benefits to outweigh the downsides, reporting that improved stability and pain control gave them back a measure of function and quality of life that they couldnt achieve otherwise

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It is necessary to optimize the formula (such as adding antioxidants) or packaging materials (such as oxygen barrier bottles) to improve stability

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Sleep promotes antioxidant production including melatonin as well as the antioxidant enzymes superoxide dismutase, catalase, and glutathione peroxidase (Gulec et al., 2012