Betsy Redmond, PhD, MMSc, RDN Instagram: @nutrition_provisions Betsy Redmond, PhD, MMSc, RDN has worked at a functional diagnostic laboratory in content development and research for more than 10 years, and also runs her own private practice nutrition & consulting business
ABC transporters (ATP-binding cassette) specially P-gp (P-glycoprotein) play an important role in clinical drug resistance by many of mechanisms for example high level expression by gene rearrangement
Furthermore, S-nitrosylation of specific targets can either promote (e.g., inhibiting GPX4) or inhibit (e.g., activating survival pathways) ferroptosis
These treatments can help combat fatigue, support cognitive function, and enhance overall wellness
Bottom line: even if the FDA eventually recommends that certain peptides can be compounded under Section 503A, many stakeholders could still be blocked by the requirement to source pharmaceutical-grade API from an FDA-registered establishment with a Certificate of Analysis and by FDAs demonstrated willingness to police marketing claims around compounded drugs
