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A UCSF article on modern vaping devices explains how efficient some modern nicotine vapes have become at delivering active compounds

Most of them are real strong, but CRUDE SS (Sweden), PSA (Italy), ANTI SYSTEM (UK), and the MAU MAUS (UK) really tear it up

This was going to prove more difficult than I had anticipated as the new version of Camel SNUS roBUST was nowhere to be found in my area

But menthol also interacts with nicotine in the brain to enhance the addictive effects of nicotine The combination of menthols taste, sensory effects and addictiveness increase the likelihood that young people who start smoking menthol cigarettes will progress to regular use

E-liquid generally includes nicotine, although nicotine-free options are available (including cannabis-derived extracts, which are outside the current topic)