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In hindlimb ischemia models, the peptide accelerates blood flow recovery as measured by laser Doppler scanning, with histological analysis confirming increased vessel numbers and enhanced vascular expression of VEGFR2

Per-injection doses are larger (usually 2 to 5 milligrams) but the total weekly peptide load is roughly comparable to BPC-157 by cost

Regulators, therefore, treat it differently from medications requiring strict prescriptions

The peptide's stability profile allows for both oral and parenteral administration, with documented biological activity through multiple delivery routes including subcutaneous, intramuscular, intraperitoneal, and oral administration

PMID: 208 XinXWangQQingJSongWGuiYLiXet al