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Received: Accepted: Published: Version of record: DOI:

Variable Bioavailability: Oral dosing may result in inconsistent absorption, affecting effectiveness or tolerability

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While it seems intuitive to massage the area, rubbing can increase bruising and irritation

Similarly, no clinically significant ARA 290-related alterations of baseline biochemical (electrolytes, calcium, liver, kidney or pancreas) or hematological (erythrocyte, thrombocyte or leukocyte) parameters were observed