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As a general guideline for the protection of public health, the US EPA establishes a threshold range for tolerable risk between 1.00E-4 and 1.00E-6 (i.e., the likelihood that an individual will develop cancer from lifetime exposure to a carcinogen is 1 in 10,000 to 1 in 100,000) [9, 42, 43]

Impact of chronic obstructive pulmonary disease on mortality: a large national cohort study

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For a while he fell out of the zeitgeist, but his career was revived in 1975 when he starred in Neil Simon's "The Sunshine Boys" opposite Walter Mathau, for which Burns earned an Oscar and a Golden Globe

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