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Each patient and surgery is unique

Among them, Als3, as a hypha-specific surface protein, can bind to host cadherins to induce endocytosis, mediate adhesion and colonization, invasion, and participate in iron metabolism to enhance pathogenicity (Liu and Filler, 2011)

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256 Understanding the molecular mechanisms underlying the adaptation of the ACL to mechanical stress can inform the development of personalized training and rehabilitation programs that optimize the mechanical loading conditions to enhance ligament strength and reduce the risk of injury