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In general, the diagnosis is clinical and no laboratory tests or biopsies are required

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Persson AK, Thun J, Xu XJ, Wiesenfeld-Hallin Z, Strm M, Devor M, et al

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In addition to the drugs that ameliorate inflammation in GA by targeting TLRs, sparsolonin B inhibited FA-induced macrophage inflammation in an osteoarthritis model by selectively blocking the TLR4/MD-2/NF-B axis (177)