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Advanced / Aggressive Approach (2 mL = ~5,000 mcg/mL) Reconstitute: Add 2.0 mL bacteriostatic water to one 10 mg vial final concentration: ~5,000 mcg/mL

Journal of Orthopaedic Research

TB-500 is a synthetic version of a naturally occurring protein called thymosin beta-4

In those preclinical models it has been reported to promote angiogenesis the growth of new blood vessels through the VEGFR2AkteNOS / nitric-oxide pathway, which may help explain its observed effects on healing [1] [4]

Experimental vascular studies using isolated rat aorta preparations reported that BPC-157 modulated vasomotor tone and increased nitric oxide generation through activation of the SrcCaveolin-1endothelial nitric oxide synthase (eNOS) signaling pathway [3]