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During early childhood, he presented myopia, easy bruising, and fragility of the facial skin, with several facial skin lacerations after minor trauma

10.1021/acsomega.2c00972 86 WangT.WangH.LiuH.WangL.WangR., (2006)

All analyses were performed using ImageJ software

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The latter is defined as failure of adequate trials of two tolerated, appropriately chosen and used antiepileptic drug (AED) schedules (whether as monotherapies or in combination) to achieve sustained seizure freedom 2