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As described previously, stimulation of thermogenesis in iBAT occurs through stimulation of UCP1 (expression of uncoupling protein 1) and activation of UCP1-independent metabolic pathways

[16] Although cyanocobalamin lacks a defined upper-toxicity threshold due to its water solubility and renal elimination, exceptionally high cumulative doses have been temporally associated with acneiform eruptions, altered potassium homeostasis, and theoretical thrombotic risk, emphasizing the importance of evidence-based dosing

Abstract The glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital component of the G protein-coupled receptor (GPCR) family and is found primarily on the surfaces of various cell types within the human body

Park SA (2011) A common pathogenic mechanism linking type-2 diabetes and Alzheimers disease: evidence from animal models

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