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doi: 10.1073/pnas.1710329115 126

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A rather simple but very effective method of removing dominant epitopes to enhance responses to conserved subdominant epitopes involved the removal of the S1 portion of spike containing the RBD and then the administration of a vaccine with only S2 as a DNA vaccine or protein [73] (Table 2)

BPC-157 retains biological activity when administered orally via gavage in rodent studies, which is attributed to its remarkable stability in gastric juice