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GSH-regulated tumor cell ferroptosis and mechanism study Based on the above research results, NSBSO showed a very strong selective killing ability of tumor cells by exhausting GSH and inhibiting GSH synthesis

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Of note, MD simulation using Desmond algorithm has been reported significantly to capture the small molecule distinguishing and attaching to a receptor using long and unbiased MD simulation, which was typically identical to the experimentally defined crystal structure 75

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By reducing adipose tissue mass, improving lipid profiles, and enhancing mitochondrial function, NNMT inhibition addresses multiple pathways involved in metabolic syndrome development