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In intestinal epithelial cells of DSS-induced colitis mice, downregulation of the Nrf2-GPx4 signaling pathway promotes ferroptosis, while Furin protease can inhibit ferroptosis and protect intestinal epithelial cells by activating the Nrf2-GPx4 signaling pathway [282, 283]

Glycine is a precursor for glutathione (GSH) biosynthesis, and GSH is the predominant antioxidant molecule within cells 7

As a result, chemotherapeutics become ineffective in killing both the normal cells and tumour cells

Reeve WG, Tiwari RP, Dilworth MJ, Glenn AR

Table 2 shows that the pro-BDNF kits from the three brands tested showed negligible cross-reactivity with mBDNF: 1.3% (#DY3175, R& Systems), 1.5% (#EH4255, FineTest) and 1.7% (#SK00752-09, Aviscera Bioscience)