Co-inheritance of Gilberts syndrome along with the above hematologic abnormalities is associated with an increased incidence of hyperbilirubinemia in neonates and older individuals
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Any insoluble material was pelleted by centrifugation (13,000 g , 10 min, 4 C) and then 100 l of supernatant CL was transferred to a clean microcentrifuge tube
The BIOM file output from the DADA2 pipeline and the DECIPHER-aligned FastTree phylogenetic tree were input into QIIME (v1.9.1) and the scripts in the Supplementary Materials (QIIME Scripts compilation) were used to establish the alpha diversity metrics of Chao1 richness estimate, Simpsons evenness measure E, Shannon diversity index H, Simpsons diversity index, and Faiths phylogenetic diversity metric (whole tree) as well as the beta diversity measures of unweighted and weighted UniFrac analyses (the latter of which factors in ASV abundance 37 ) and BrayCurtis dissimilarity analysis
Data availability statement The original contributions presented in the study are included in the article/Supplementary Material, further inquiries can be directed to the corresponding authors