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Oxid Med Cell Longev 2012 (PMC3359723) Bertini I et al

Starting at 1.0 mg significantly increases the risk of nausea, vomiting, and other gastrointestinal side effects

However, its important to keep one foot on the ground: while results have been encouraging, scientists and dermatologists agree that larger, longer-term studies are still needed to truly understand the long-term safety and effectiveness of peptide therapy

Participants with obesity who received the 12mg dose lost an average of 28.7% of their body weight at 68 weeks, translating to an average of 71.2 pounds from a baseline weight of approximately 248 pounds

Moderate, regular exercise supports treatment outcomes better than extreme regimens