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The cut-off concentration (or decision concentration) for hypobilirubinemia reported in the literature varies, so studies to establish a reliable concentration have not yet been completed ( 78 )

Exogenous -aminobutyric acid alleviates oxidative damage caused by aluminium and proton stresses on barley seedlings

at the same time, changes in intracellular Ca 2+ lead to the opening of neuronal pannexin 1 channels to open and activate cystatinase 1, followed by the release of high mobility group box-1 protein and the activation of nuclear factor kappa-B signaling pathway in astrocytes (Karatas et al., 2013), which triggers substantial inflammatory response, producing a variety of inflammatory cytokines such as interleukin (IL)-1 (Figure 1B)

doi: 10.3390/ani13081274 162