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You're hitting mitochondrial health from two angles simultaneously: MOTS-C improves mitochondrial efficiency and increases fat oxidation NAD+ replenishes the coenzyme required for ATP synthesis For anyone over 40 who's training seriously, this pairing addresses two of the most significant age-related performance bottlenecks at once

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Quercetin inhibits hippocampal ferroptosis in diabetic encephalopathy by binding KEAP1 and upregulating the Nrf2/HO-1 pathway, reducing lipid peroxidation and iron deposition (Ren et al., 2025)

The American journal of pathology, 168(6), 18611868