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We found that pharmacological MT1 and MT2 agonism failed to replicate the effects of melatonin in suppressing IL-5 production ( Figures 3B, D ) or IL-13 production ( Figures 3C, E )

10.1016/j.lungcan.2012.05.107 Lung Cancer Summary Keywords GSTP1, cancer, epigenetics, DNA methylation, histone modifications, epimutations, biomarker Citation Schnekenburger M, Karius T and Diederich M (2014) Regulation of epigenetic traits of the glutathione S -transferase P1 gene: from detoxification toward cancer prevention and diagnosis

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OXPHOS requires the presence of oxygen, and oxygen conversion into water occurs in the inner mitochondrial membrane