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In vitro studies using adipocyte cell lines, including 3T3-L1 cells and primary adipocyte cultures, have used this compound to examine lipolytic signalling, triglyceride hydrolysis mechanisms, fatty acid oxidation pathways, and adipokine secretion

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As well as systemic inflammation, other possible suggested mechanisms for CAD comorbidity of psoriasis are increased prevalence of common CAD risk factors in psoriasis patients and antipsoriatic medications are suspected (cyclosporine, acitretin) for their adverse CAD risk profiles (e.g., elevation of blood pressure, elevation of serum levels of lipids)