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This process is regulated by iron homeostasis, redox balance, lipid metabolism, glutathione metabolism, and various disease signaling pathways

During the oxidation phase, accumulated ROS (such as hydrogen peroxide HO and superoxide anion O) in the cell can directly react with GSH in a non-enzymatic manner, or, under the catalysis of glutathione peroxidase (GPX), promote the oxidative coupling of two GSH molecules to form one molecule of GSSG, while releasing two protons (H) and two electrons (e)

Its primary mechanism involves delivering bioavailable copper to tissues, which activates a variety of biological responses

Wang, S.-H., Lin, L.-P., Lin, M.-S., Pang, J.-H

Research shows coffee contains powerful antioxidants that help reduce inflammation and support the immune system [11]