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Abstract Ferroptosis, a modality of regulated necrosis caused by iron-dependent lipid peroxidation, has emerged as a key contributor to the pathogenesis of acute tubular necrosis (ATN) especially in the context of solid organ transplantation

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It is intended exclusively for qualified researchers and licensed institutions performing in vitro testing or authorized non-human preclinical studies under controlled conditions

Glutathione-related enzyme and melanogenesis Modulation of the glutathione system through its key enzymes, including cystine/glutamate antiporter (xCT), GCL and GR, has also been correlated with melanin formation