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Supplemental Figure 6

For example, thioredoxins are a family of redox active proteins of approximately 12 kDa responsible for mediating numerous cytoplasmic functions influenced by available cysteine residues in the monomeric protein

in contrast, GSS knockout depletes GSH but still permits glutamate consumption for -glutamyl-peptide synthesis, and does not alter ferroptosis sensitivity under cystine starvation

Misconception 4: the CASTA trial proved cerebrolysin does not work for stroke The CASTA trial showed no overall benefit in the primary endpoint for the full population, but did show benefit in severe strokes

The FDA black box warning on antidepressant suicide risk in young adults: more harm than benefits