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Par ailleurs, les deux molcules interviennent dans des compartiments cellulaires complmentaires : toutes deux hydrosolubles, elles agissent dans le cytoplasme et les milieux extracellulaires, en synergie avec dautres acteurs du systme antioxydant endogne

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Plasmodium falciparum is primarily responsible for a significant part of the morbidity and mortality that comes from malarial infection [400]

Beyond disulfide bonds, diselenide bonds (-SeSe-) have also been employed in GSH-responsive DDSs, owing to seleniums chemical similarity to sulfur, as both elements belong to Group VI of the periodic Table [58]