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Berberine not only enriches butyrate-producing bacteria and elevates butyrate levels, thereby improving gut microbiota composition and function, (86) but also attenuates inflammatory responses and endoplasmic reticulum stress induced by HIV protease inhibitors

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On the other hand, spontaneous and often substantial functional improvements [53,54,55] after partial lesioning of the spinal cord are associated with the spontaneous sprouting of axons in the corticospinal tract [56,57,58] and the formation of neural circuits by spared spinal cord tissue [26]

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