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41,42 Lactate transport is mediated by proton-coupled monocarboxylate transporters (MCTs), encoded by the SLC16A gene family and comprising 14 transmembrane protein isoforms, among which MCT1 and MCT4 are functionally predominant

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Studies demonstrate that apigenin administration improves cognitive and memory deficits in TBI rodent models, as evidenced by enhanced performance in the Morris water maze and Step-down inhibitory avoidance tests (Zhang et al., 2015)