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Regarding potential therapeutic targets of nicotine-derived compounds, the nAChRs subtypes, 6 2 3 and 6 4 2 3, play a key role in modulating dopaminergic function in the mesolimbic and nigrostriatal dopaminergic pathways

Science of the Total Environment, 128 (1), 2135

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Mundt did not testify at the Boston trial but has written expert reports in other lawsuits saying that the conclusions of some of the nations leading tobacco experts, including the authors of the NCI report, fail to address the totality of relevant evidence and largely remain unsubstantiated. Jonathan Samet, a professor at the University of Southern Californias medical school who was asked by the NCI to be one of the reviewers of its report, said the findings went through rigorous peer review