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As a molecular sensor of mitochondrial damage, PINK1 accumulates on the outer mitochondrial membrane due to impaired transmembrane translocation upon mitochondrial membrane potential (m) depolarization (Lu et al., 2023)

The assessments of depression (HAM-D, BDI, CGI/C) revealed modest, non-significant declines across all cohorts, with sertraline exhibiting a slightly more pronounced drop in HAM-D scores (8.2) than R

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Statistics show that 35% of the UK population struggles with joint problems, with one in five individuals affected to varying degrees.Milder cases include conditions such as arthritis, rheumatism, and gout, with symptoms like pain, stiffness, swelling, fatigue, and reduced mobility