glutathione increases testosterone Injection: Is It Really Worth The Hype? Low Testosterone and Sleep Problems:

There is also a potential risk of immune responses to synthetic peptides or genetically modified strains, necessitating dedicated immunological safety assessment (Mousa et al., 2023)

Of all the tested Se compounds, the promising anticancer effects in cancer seem to be associated with Se-NPs and Na 2 SeO 3

The peptide structure is engineered to resist rapid enzymatic degradation while maintaining functional activity

Although smaller NPs often elicit stronger stimulation of antigen-presenting cells (APCs) in vivo, chemical composition and surface modifications can substantially modulate these effects [27]

that's it. But you need to figure out the root causes