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[PubMed] [Google Scholar] 59.Asai A., Sugawara T., Ono H., Nagao A

The gene-synthesized PSD95-(SH3-GK) (427-724) domain was purified using Ni 2+ -affinity chromatography (HiTrap IMAC FF, Cytiva), followed by thrombin digestion and anion-exchange chromatography (HiTrap Q FF, Cytiva)

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This outcome was associated with an inhibition of the enhanced mTOR signaling pathway in the PFC of these mice, suggesting beneficial effects of the AA diet in both genetic and idiopathic forms of ASD (93)

This gastric acid stability makes BPC-157 one of the few peptides studied for oral bioavailability, as most peptides are rapidly degraded in the digestive tract