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Ultimately, designing more targeted and effective clinical trials based on improved understanding, utilizing novel delivery systems, incorporating validated biomarkers, and focusing on specific patient subgroups will be critical for successfully translating research findings into improved outcomes for MIRI patients

On the other hand, cell-based delivery methodologies are also under investigation, including the utilization of stem cells or genetically modified immune cells as vehicles to transport therapeutic agents to the brain, leveraging their innate homing capabilities and ability to traverse the BBB

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(2020) formulated lipid-polymer nanoparticles (LPN) and employed them to encapsulate and safeguard astaxanthin (ATX)

30 , 477492.e6 (2019)