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Despite differing pathologies, these conditions share a common feature: rumen microbial imbalance and altered metabolic function

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European Journal of Nutrition vol

Hopkins F.G

additionally, GPX4 can inhibits the phospholipid peroxidation of adipocytes, although the specific mechanism is unclear ( / AT mice, and spontaneously produced impaired insulin signaling in the liver, resulting in systemic inflammation and disorders of glucose metabolism ( FSP1 Ferroptosis-suppressor-protein 1 (FSP1) is a recently discovered non-GPX4-dependent ferroptosis inhibitory factor, which exhibits a different pathway of action from GPX4 in the process of ferroptosis inhibition, mainly regulated by the NAD (P)H/FSP1/CoQ10 system ( Figure 1C )