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1996 Oct;91(10):21103

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Long-term GH elevation also carries theoretical cancer concerns, as GH and IGF-1 can promote cell growth

In a real-world cohort, six-month semaglutide loss was about 8.8%, roughly 0.6 to 0.8 of the STEP figure, mostly through adherence and persistence rather than a weaker drug. Read the trial number as a ceiling to translate down toward your own body and your own consistency, not as a forecast