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Preclinical research suggests TIMP-1 is implicated in fear and memory processes (80), and has shown to have a protective role in neurodegenerative disorder (81)

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In animal models, where depression was induced by lipopolysaccharide, which is an inflammatory compound, BSO reduces that lipopolysaccharide-induced inflammation and alleviates depressive behaviors

Estradiol inhibits plasma somatostatin 14 (SRIF14) levels and inhibits the response of somatotrophic cells to SRIF14 challenge in vitro in rainbow trout, Oncorhynchus mykiss

Additionally, CCCP has demonstrated protective effects on the microvascular system by activating the PINK/Parkin pathway to inhibit inflammation, thereby alleviating coronary no-reflow