In experiments examining smokers MLE to Tar and Nicotine ANOVA GLM, with subject as a random factor, was used to compare smokers MLE to tar and nicotine obtained for the control and split tipping products within each ISO pack tar group
One reason the levels of 1a-d are higher herein is that we used the harsher 50 puff replication study puffing regimen, which the researchers performing the latter study had modified 4 (without explanation) from our original milder 10 puff experiments
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