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The chart below outlines evidence-aligned recommendations

Choosing the injection site

121 ZntR plays a key role specifically in Brucella abortus Zn II homeostasis

Although we have focused on the mitochondria as we believe that this core respiratory deficiency is the most important example of a copper-dependent system as it governs metabolism (Ruiz et al., 2021), it is necessary to point out the key role of other copper-dependent systems that would be compromised in the brain-wide copper deficiency we see in AD