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In some embodiments, the otic formulation or composition comprises about 20% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

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Research in Pharmaceuticals (MDPI, 2025) reviews BPC-157's mechanisms across tissue injury and repair models, documenting its effects via VEGFR2-Akt-eNOS angiogenic pathways, nitric oxide signaling, and growth hormone receptor expression upregulation in tendon fibroblasts

For example, one experiment in rabbits suggested that DSIP may help reduce electrical instability of the heart in emotional stress and mitigate stress-related events such as extrasystoles [7]