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The Boc-protected cystine-1,1- 13 C was reacted with two equivalents of glycine tert -butyl ester (OtBu) hydrochloride using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide monohydrochloride and 1-hydroxybenzotriazole to produce the N and C-protected dipeptidyl (Boc-Cys-Gly-OtBu) disulfide derivative

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Nicotine also produces more pronounced behavioral sensitization in female than male rats ( Astrocytes are glial cells that regulate the cellular absorption and release of glutamate, e.g., glutamate homeostasis, thereby affecting the development of drug dependence (Veruki et al., 2006)