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10.1002/jcb.22580 62 LuoJ.ChenR.ZengS.YuJ.JiangG.WangL.et al (2017)

This means topical copper peptide formulations need precise concentration targeting

Oxidative stress is a critical factor in inducing the release of chemokines from keratinocytes that direct CD8+ T cells and lead to migration into skin tissue, causing melanocyte death [20]

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Future studies should optimize material design, develop novel safety assessment methods, and promote interdisciplinary collaboration for clinical translation