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ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43

Incorporating different bile acids and other gut-specific metabolites into future studies may shed light on biofilm regulation in a wider range of strains and species, with potential implications for functional engineering of the human gut microbiota

The identification of predictive biomarkers could further optimize these combination strategies (114, 115)

Paracetamol represents an excellent first-line choice for mild to moderate pain relief in patients using Wegovy

In a phase 2 trial of obese subjects, cagrilintide used in different subcutaneous doses once weekly was associated with a mean weight loss of 6-10.8% after 26 weeks, compared with 9.0% with the glucagon-like 1 receptor (GLP-1R) liraglutide (3 mg/d) and 3% with placebo at 26 weeks