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The BMP/Smad pathway effect is counteracted by the transplantation of MSCs derived from bone marrow (BMSCs), which promote NSC differentiation into OLs, the myelinating glia of the CNS (Sandner et al., 2013

But that delicate structure, so carefully preserved, is also incredibly vulnerable when its time to wake it up

A typical acute injury protocol begins with 0.25 mg twice daily for the first week, reduces to 0.5 mg once daily for weeks two through four, then continues at 0.25 mg daily for weeks five and six if needed

And when you do, your immune system will thank you

What Success Looks Like Realistic expectations: 30-40% improvement in density