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JOE BETTS-LACROIX, CEO RETRO BIOSCIENCES: I'm very specifically focused on how to apply our new, especially academic understanding of how aging works to finding new therapeutics that we can make medicines out of

Used in explaining increased frequency of seizures in epilepsy and progression of bipolar disorder in humans. Jason et al have recently (2011) proposed kindling as an etiological model for ME/CFS : Kindling might represent a heuristic model for understanding the etiology of Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS)

Continuous data collected from the participants over the 26 week treatment period was assessed using an ANCOVA model, using randomized treatment as a factor and baseline bodyweight as a covariate

The key difference is in dosing, as tirzepatide escalation starts at 2.5mg rather than 0.25mg, which means much larger weekly doses and faster vial consumption

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